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Courtesy of Professor Ashim K. Datta, Dept. of Biological
& Environmental Engineering, Cornell University
Students from the Department of Biological & Environmental Engineering
of Cornell University in Ithaca, NY have been using FIDAP to simulate
biomedical applications as part of a junior-senior level course, which
has been taught for six years. During the course, students are taught
about methods for solving systems of equations, including the finite element
method used in FIDAP. They are trained to use FIDAP through the use of
lectures and hands-on examples created by the faculty. Graduate teaching
assistants with a knowledge of CFD have served a vital role over the years
in teaching students how to use FIDAP and in providing debugging assistance
on the individual projects. Towards the end of the course, the students
review carefully chosen computational case studies from the literature
in areas of bio-medical engineering and food processing.
The students then divide into teams to work on separate independent projects.
They choose the biomedical examples that are to serve as project topics,
and claim that this selection process is one of the most rewarding aspects
of the course. The FIDAP simulations are performed on one of four departmental
machines, supplied by a grant from Intel. In the past, super-computers
at the Cornell Theory Center have also been used.
Numerous applications have been simulated by the students in the course
during recent years. In one example 1 (Figure
1), heat transfer to the cornea was examined during laser surgery
procedures to correct either myopia (nearsightedness) or hyperopia (farsightedness).
Operations using a single laser beam were compared to those using multiple
laser beams. Through their simulations, the students optimized the laser
beam shape and were able to obtain good images of the resulting temperature
distributions. Knowledge of the temperature distribution could minimize
the risk of failure during the actual operation. For example, when the
laser is applied at multiple locations, the surgeon has better control
of the heat flux delivered, and the procedure can be completed in a shorter
time.

Figure 1: Temperature contours on the surface of the cornea following
laser surgery with a single off-center laser (top) used to treat myopia,
and multiple lasers (bottom) used to treat hyperopia
In another example 2 (Figure 2), the
temperature profile in the prostate gland was studied during cryogenic
surgery to destroy a tumor. When applied to the prostate, cryosurgery
is claimed to have fewer side effects than radiation or surgical removal.
The benefits include less blood loss, fewer incisions, and faster recovery.
During the procedure, the surrounding good tissue should be affected only
slightly. The students found that using one probe to freeze the entire
tumor is impractical.

Figure 2: Temperature vs. time in a prostate tumor cooled using one, three,
and five probes
Because the tumor is not a good thermal conductor, a long period of time
is needed to destroy it, and a significant amount of destruction occurs
in the good tissue surrounding the site during this time. By using more
probes, the tumor can be cooled more uniformly and with less damage to
the surrounding good tissue. They also found that colder cryogens are
best because they help to localize the freezing.
In a third example 3 (Figure 3), transient
heat transfer during a tooth drilling procedure was studied. For three
drill speeds, a thermal boundary condition was computed separately as
a function of frictional effects. Cooling water over the tooth was used
to modify this boundary condition. Using FIDAP, transient temperature
prof iles in the tooth were computed as the hole was allowed to grow (through
the use of the moving boundary model). The high-speed drill was found
to be preferable, since it led to a quicker procedure, resulting in less
heat transfer to the base of the tooth, with the likelihood of reducing
pain sensation.

Figure 3: Temperature contours in a tooth after a high-speed drilling
procedure
The course has been helpful in exposing students to simulation-based
engineering. It shows how simulation can be used to speed up the design
process. It gives them a depth of understanding about bio-medical processes
that they cannot get without doing the detailed computations. Through
the project work, the students learn about the sensitivity of CFD results
to choices of input and solution parameters, such as boundary conditions
or convergence level. While they do not leave the class claiming to be
experts in CFD or numerical methods, the experience does play a significant
role on their resumés as they begin searching for jobs after graduation.
Example References:
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Chih Hao Chen, Diana Chen, Kim Foo Chow, JenYee Hui, and Darrick
Lo
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Brian Chow, Ingar Lau, Mike Neidrauer, and Jennifer Park
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Julian Mintseris, Yuri Bunimovich, Vivek Mohan, and Becky Kim
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